DRKS00029146

miRNAs with highly variable expression in human immune cells

Hummingbird Diagnostics GmbHIm Neuenheimer Feld 58369120 HeidelbergGermany·Deutsches Register Klinischer StudienNot yet recruiting
Study focus
Disease/Condition
None ;Healthy volunteers
Study type
Observational
Sponsor & location
Primary sponsor
Hummingbird Diagnostics GmbHIm Neuenheimer Feld 58369120 HeidelbergGermany
Location
Germany
Timeline & enrollment
Phase
N/A
Start date
N/A
End date
N/A
Summary

One of the promising biomarker classes for diagnosis and prognosis of various diseases is that of short-chain non-coding microRNAs (miRNA), which have been shown to be reliable indicators of cell as well as immune status. Through this study, we aim to further determine the function of miRNAs with highly variable expression ("variable miRNAs"), which, according to preliminary data, exhibit variable expression and are positively correlated with the number of regulatory T cells. Here, we will examine whether variable miRNAs regulate the generation of CD4+ regulatory T cells by inhibiting mTOR activity.

ICD-10 classifications
Healthy person accompanying sick personRoutine general health check-up of armed forcesRoutine general health check-up of sports teamsRoutine general health check-up of inhabitants of institutions
Data source
Registry
Deutsches Register Klinischer Studien
Trial ID
DRKS00029146
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for DRKS00029146 through Pure Global AI's free database. This phase not specified trial is sponsored by Hummingbird Diagnostics GmbHIm Neuenheimer Feld 58369120 HeidelbergGermany and is currently Not yet recruiting. The study focuses on None ;Healthy volunteers.

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