Release of Osteogenic Markers in Immediately and Non-loaded Dental Implants - Trial NCT01909999
Access comprehensive clinical trial information for NCT01909999 through Pure Global AI's free database. This phase not specified trial is sponsored by Renato Correa Viana Casarin and is currently Completed. The study focuses on Jaw, Edentulous. Target enrollment is 40 participants.
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Study Focus
Sponsor & Location
Renato Correa Viana Casarin
Paulista University
Timeline & Enrollment
N/A
Mar 01, 2010
Dec 01, 2012
Primary Outcome
Ostegenic markers concentration
Summary
The aim of this study was to compare the release of the osteoprotegerin (OPG), transforming
 growth factors (TGF-ฮฑ), osteocalcin (OCN), osteopontin (OPN), and parathyroid hormone (PTH)
 during osseointegration of dental implants with and without immediate loading. Forty patients
 were selected and randomly divided into: Group IM - implant and prosthesis placement within
 72 hours; and Group NL - implant insertion and no prosthesis placement during 120 days.
 Peri-implant crevicular fluid (PICF) was collected immediately after implant insertion and
 with 7, 15, 30, 60, 90, and 120 days after surgery and were evaluated levels of OPG, TGF-ฮฑ,
 OCN, OPN and PTH using Luminex assay. Clinical aspects (Sulcus bleeding and peri-implant
 probing depth) were also assessed. The data were compared using the ANOVA/Tukey and
 Friedman/Mann-Whitney tests (ฮฑ=5%).
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT01909999
Non-Device Trial