NCT01909999

Release of Osteogenic Markers in Immediately and Non-loaded Dental Implants

Name: Clinical Trial NCT01909999
Creator: Renato Correa Viana Casarin
Keywords: Jaw, Edentulous, Osteogenic markers Evaluation, procedure, clinical trial, Brazil

Renato Correa Viana Casarin·ClinicalTrials.gov·procedureCompleted

View on ClinicalTrials.gov →

Study focus

Disease/Condition: Jaw, Edentulous
Drug/Device/Intervention: Osteogenic markers Evaluation
Study type: Interventional
Intervention type: procedure

Sponsor & location

Primary sponsor: Renato Correa Viana Casarin
Funder: Paulista University
Location: São Paulo, Brazil

Timeline & enrollment

Phase: N/A
Start date: Mar 01, 2010
End date: Dec 01, 2012
Enrollment: 40 participants

Primary outcome

Ostegenic markers concentration

Summary

The aim of this study was to compare the release of the osteoprotegerin (OPG), transforming growth factors (TGF-α), osteocalcin (OCN), osteopontin (OPN), and parathyroid hormone (PTH) during osseointegration of dental implants with and without immediate loading. Forty patients were selected and randomly divided into: Group IM - implant and prosthesis placement within 72 hours; and Group NL - implant insertion and no prosthesis placement during 120 days. Peri-implant crevicular fluid (PICF) was collected immediately after implant insertion and with 7, 15, 30, 60, 90, and 120 days after surgery and were evaluated levels of OPG, TGF-α, OCN, OPN and PTH using Luminex assay. Clinical aspects (Sulcus bleeding and peri-implant probing depth) were also assessed. The data were compared using the ANOVA/Tukey and Friedman/Mann-Whitney tests (α=5%).

ICD-10 classifications

Dislocation of jawMottled teethDisorder of gingiva and edentulous alveolar ridge, unspecifiedOther disorders of gingiva and edentulous alveolar ridgeOther specified disorders of gingiva and edentulous alveolar ridge

Data source

Registry: ClinicalTrials.gov
Trial ID: NCT01909999
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for NCT01909999 through Pure Global AI's free database. This phase not specified trial is sponsored by Renato Correa Viana Casarin and is currently Completed. The study focuses on Jaw, Edentulous. Target enrollment is 40 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.