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Effect of Vit D on New-onset AF in Hypertension - Trial NCT02298738

Access comprehensive clinical trial information for NCT02298738 through Pure Global AI's free database. This phase not specified trial is sponsored by Ankara University and is currently Completed. The study focuses on Atrial Fibrillation,Hypertension. Target enrollment is 227 participants.

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NCT02298738
Completed
Trial Details
ClinicalTrials.gov โ€ข NCT02298738
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Effect of Vit D on New-onset AF in Hypertension
Relation of Low Vitamin D Levels and New-onset AF Among Hypertensive Patients

Study Focus

Observational

Sponsor & Location

Ankara University

Timeline & Enrollment

N/A

Jan 01, 2012

Nov 01, 2014

227 participants

Primary Outcome

hypovitaminosis D

Summary

Atrial fibrillation (AF), an important cause of cardiac mortality and morbidity is the most
 common type of cardiac arrhythmia in clinical practice. Hypertensive individuals are at
 particular risk of development of atrial fibrillation. Renin-angiotensin-aldosteron system
 (RAS) which is activated in hypertension may be the underlying mechanism of AF among
 hypertensive patients.
 
 Vitamin D deficiency has been shown to be involved in the pathogenesis of hypertension,
 cardiovascular disease and obesity. Increased RAS activity is one of the postulated
 mechanisms by which vitamin D deficiency may trigger the development of hypertension and
 various cardiovascular diseases. On the basis of these data we hypothesized that
 hypovitaminosis D might be associated with new-onset AF among patients with hypertension.

ICD-10 Classifications

Chronic atrial fibrillation
Persistent atrial fibrillation
Paroxysmal atrial fibrillation
Atrial fibrillation and flutter
Atrial fibrillation and atrial flutter, unspecified

Data Source

ClinicalTrials.gov

NCT02298738

Non-Device Trial