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NCT02356900

Hyperbaric VO2max Study

Effects of High Intensity Interval Training in a Hyperoxic-hyperbaric Environment on Exercise Performance at Altitude
Duke University·Phase 2·ClinicalTrials.gov·procedureTerminated
View on ClinicalTrials.gov →
Study focus
Disease/Condition
Exercise Training
Drug/Device/Intervention
Hyperoxic hyperbaric interval exercise training
Study type
Interventional
Intervention type
procedure
Sponsor & location
Primary sponsor
Duke University
Location
Durham, United States of America
Timeline & enrollment
Phase
Phase 2
Start date
Feb 01, 2015
End date
May 01, 2016
Enrollment
25 participants
Primary outcome

Change in Maximum Aerobic Capacity (VO2max) From Baseline to Post-training ( 72 Hours ),Change in Ventilatory Threshold (VT) From Baseline to Post-training (72 Hours),Mitochondrial Mass Change,Tfam Muscle Protein Content Change,Pgc-1a Coactivator Muscle Protein Content Change,COX-I Gene Expression Change,Muscle Phenotype Change

Summary

This study seeks to examine the effectiveness of training while in a hyperoxic-hyperbaric
 environment for exercise performance at altitude. Subjects will complete a short,
 high-intensity interval training (HIT) program inside the hyperbaric chamber.Before and after
 this training phase, all subjects will be tested for maximum aerobic capacity at a simulated
 high altitude of 15,000ft in a hypobaric chamber, as well as for molecular markers of
 mitochondrial oxidative capacity in a skeletal muscle biopsy.
 
 A group of individuals of similar characteristics completing this training program in a
 normoxic-normobaric environment will serve as a control.

ICD-10 classifications
Orthoptic trainingLack of physical exerciseOther physical therapyCardiac rehabilitationExhaustion due to excessive exertion
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT02356900
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT02356900 through Pure Global AI's free database. This Phase 2 trial is sponsored by Duke University and is currently Terminated. The study focuses on Exercise Training. Target enrollment is 25 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.