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Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis (EVOCAR-1) - Trial NCT03931161

Access comprehensive clinical trial information for NCT03931161 through Pure Global AI's free database. This Phase 4 trial is sponsored by Imperial College Healthcare NHS Trust and is currently Recruiting. The study focuses on Carotid Artery Stenosis. Target enrollment is 60 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT03931161
Phase 4
Recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT03931161
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Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis (EVOCAR-1)
Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis

Study Focus

Carotid Artery Stenosis

Evolocumab Auto-Injector [Repatha]

Interventional

drug

Sponsor & Location

Imperial College Healthcare NHS Trust

London, United Kingdom

Timeline & Enrollment

Phase 4

Sep 04, 2019

Sep 04, 2023

60 participants

Primary Outcome

Change in lipid-rich necrotic core

Summary

This is a phase IV, randomised, placebo-controlled, double-blind, parallel group study to
 determine the effect of Evolocumab treatment on carotid plaque morphology and composition in
 asymptomatic patients with 50% carotid artery stenosis.

ICD-10 Classifications

Occlusion and stenosis of carotid artery
Carotid artery syndrome (hemispheric)
Injury of carotid artery
Aneurysm and dissection of carotid artery
Occlusion and stenosis of vertebral artery

Data Source

ClinicalTrials.gov

NCT03931161

Non-Device Trial