Pragmatic Urinary Sodium-based Treatment algoritHm in Acute Heart Failure - Trial NCT04606927
Access comprehensive clinical trial information for NCT04606927 through Pure Global AI's free database. This phase not specified trial is sponsored by University Medical Center Groningen and is currently Recruiting. The study focuses on Heart Failure Acute. Target enrollment is 310 participants.
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Study Focus
Sponsor & Location
University Medical Center Groningen
Timeline & Enrollment
N/A
Feb 01, 2021
Jun 01, 2024
Primary Outcome
Total natriuresis after 24 hours,First occurrence of all-cause mortality or heart failure rehospitalization after 180 days
Summary
Administration of loop diuretics to achieve decongestion is the current cornerstone of
 therapy for acute heart failure. Unfortunately, there is a lack of evidence of how to guide
 diuretic treatment. Recently, urinary sodium, as a response measure of diuretic response, has
 been proposed as a target for therapy. The hypothesis of this study is that natriuresis
 guided therapy in patients with acute heart failure will improve diuretic response,
 decongestion, and reduce length of hospital stay, as well as heart failure
 rehospitalisations.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT04606927
Non-Device Trial