Pragmatic Urinary Sodium-based Treatment algoritHm in Acute Heart Failure
- Disease/Condition
- Heart Failure Acute
- Drug/Device/Intervention
- Natriuresis
- Study type
- Interventional
- Intervention type
- other
- Primary sponsor
- University Medical Center Groningen
- Location
- Groningen, Netherlands
- Phase
- N/A
- Start date
- Feb 01, 2021
- End date
- Jun 01, 2024
- Enrollment
- 310 participants
Total natriuresis after 24 hours,First occurrence of all-cause mortality or heart failure rehospitalization after 180 days
Administration of loop diuretics to achieve decongestion is the current cornerstone of
 therapy for acute heart failure. Unfortunately, there is a lack of evidence of how to guide
 diuretic treatment. Recently, urinary sodium, as a response measure of diuretic response, has
 been proposed as a target for therapy. The hypothesis of this study is that natriuresis
 guided therapy in patients with acute heart failure will improve diuretic response,
 decongestion, and reduce length of hospital stay, as well as heart failure
 rehospitalisations.
- Registry
- ClinicalTrials.gov
- Trial ID
- NCT04606927
- Type
- Non-Device Trial
Access comprehensive clinical trial information for NCT04606927 through Pure Global AI's free database. This phase not specified trial is sponsored by University Medical Center Groningen and is currently Recruiting. The study focuses on Heart Failure Acute. Target enrollment is 310 participants.
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