Safety and Efficacy of a New Transepithelial Photorefractive Keratectomy Treatment

Absolute refractive predictability

This is a prospective, comparative, randomized, controlled, single-blind, single-surgeon,
 single-center PMCF clinical study whereby participants undergoing refractive surgery for
 correction of ametropia will receive a transepithelial PRK (tPRK) and conventional PRK
 treatment in the contralateral eye. To avoid bias in the clinical outcomes, the two PRK
 treatment options are randomized to the eyes of the patients based on ocular dominance. In
 addition, a 1:1 randomization is applied within the tPRK group to eyes with and without
 end-treatment laser polishing.
 
 Both procedures, standard PRK and tPRK, are performed in a one-step procedure. The main
 difference between the procedures is, that in conventional PRK, the epithelium will be
 removed using alcohol, whereas in tPRK procedures, the epithelium will be removed by laser
 ablation.