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NCT04844190

Use of EndoFLIP and Manometry Prior to G-POEM

Use of Endoscopic Functional Lumen Imaging Probe (EndoFLIP) and Antroduodenal Manometry (ADM) in Predicting Clinical Response to Gastric Peroral Endoscopic Myotomy (G-POEM): A Pilot Study
Northwestern University·ClinicalTrials.gov·diagnostic testRecruiting
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Study focus
Disease/Condition
Gastroparesis
Drug/Device/Intervention
EndoFLIP
Study type
Interventional
Intervention type
diagnostic test
Sponsor & location
Primary sponsor
Northwestern University
Location
Chicago, United States of America
Timeline & enrollment
Phase
N/A
Start date
Apr 15, 2021
End date
Dec 31, 2024
Enrollment
20 participants
Primary outcome

Predictive Value of EndoFLIP,Predictive Value of ADM

Summary

The purpose of this study is to assess physiologic response of therapy in patients with
 refractory gastroparesis undergoing Gastric per-oral endoscopic myotomy (G-POEM) using
 endoscopic functional lumen imaging probe (EndoFLIP) and antroduodenal manometry (ADM).
 Refractory gastroparesis will be defined as having delayed gastric emptying at four hours
 (10% retention of stomach contents) on gastric scintigraphy and persistent symptoms despite
 treatment with dietary modification or prokinetic medications. We hypothesize that EndoFLIP
 and high resolution ADM will provide an individualized pyloric functional profile in
 gastroparesis patients that can more accurately predict clinical response to G-POEM.

ICD-10 classifications
Attention to gastrostomyGastrostomy statusOther gastritisGastritis, unspecifiedGastric diverticulum
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT04844190
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT04844190 through Pure Global AI's free database. This phase not specified trial is sponsored by Northwestern University and is currently Recruiting. The study focuses on Gastroparesis. Target enrollment is 20 participants.

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