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NCT04941963

Ultrasound Assessment of Diaphragmatic Function in Infants With BPD

Functional Evaluation of the Diaphragm With Bedside Ultrasound in Infants With Bronchopulmonary Dysplasia: a Single Centre Prospective Trial
Mount Sinai Hospital, Canada·ClinicalTrials.gov·otherRecruiting
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Study focus
Disease/Condition
Bronchopulmonary Dysplasia
Drug/Device/Intervention
No intervention
Study type
Observational
Intervention type
other
Sponsor & location
Primary sponsor
Mount Sinai Hospital, Canada
Location
Toronto, Canada
Timeline & enrollment
Phase
N/A
Start date
Nov 26, 2019
End date
Dec 15, 2021
Enrollment
100 participants
Primary outcome

Evaluation of the diaphragmatic Thickness fraction and diaphragmatic excursion in neonates with bronchopulmonary dysplasia

Summary

Extremely preterm infants have high and prolonged exposure to positive pressure ventilation,
 which contributes to acute lung injury and the development of bronchopulmonary dysplasia
 (BPD). Despite the risk of diaphragmatic dysfunction in infants with BPD, the effect of
 prolonged ventilator support on the diaphragmatic function of preterm infants has not been
 well characterized.
 
 Hence, we aim to characterize the diaphragmatic function of very preterm neonates with BPD
 who are corrected to ≥ 36 weeks using bedside ultrasound in comparison to healthy newborns
 born at ≥ 36 weeks gestation.

ICD-10 classifications
Bronchopulmonary dysplasia originating in the perinatal periodCongenital bronchomalaciaBronchopneumonia, unspecifiedOther congenital malformations of bronchusDiseases of bronchus, not elsewhere classified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT04941963
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT04941963 through Pure Global AI's free database. This phase not specified trial is sponsored by Mount Sinai Hospital, Canada and is currently Recruiting. The study focuses on Bronchopulmonary Dysplasia. Target enrollment is 100 participants.

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