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NCT05006807

Comparison Neuromuscular Blockade Monitors

Comparative Assessment of Neuromuscular Blockade Monitors
University of Washington·ClinicalTrials.gov·device·Device trialRecruiting
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Study focus
Disease/Condition
Neuromuscular Blockade
Drug/Device/Intervention
Mechanomyograph Twitch Monitor
Study type
Observational
Intervention type
device
Sponsor & location
Primary sponsor
University of Washington
Location
Seattle, United States of America
Timeline & enrollment
Phase
N/A
Start date
Feb 01, 2022
End date
Jun 30, 2024
Enrollment
100 participants
Primary outcome

Train-of-four count,Train-of-four ratio,Post tetanic count,Twitch count by palpation

Summary

The overall objective of this research is to evaluate different laboratory-built and
 commercially available sensors used to measure the effects of neuromuscular blocking drugs on
 neuromuscular function during surgery, by measuring evoked thumb twitch response to ulnar
 nerve stimulation (also known as twitch monitoring). The specific aim is to compare
 mechanomyography, which is the gold standard laboratory measurement to assess neuromuscular
 blockade, to the sensors used in commercially available neuromuscular blockade monitors, such
 as acceleromyography and electromyography. The study endpoints are the train-of-four count
 (TOFC), the ratio of the height of the 4th twitch to the height of the 1st twitch
 (train-of-four ratio, TOFR), and the post tetanic count (PTC). The mechanomyography devices
 have been constructed in our laboratory and are not commercially available.

ICD-10 classifications
Skeletal muscle relaxants [neuromuscular blocking agents]Poisoning: Skeletal muscle relaxants [neuromuscular blocking agents]Other neuromuscular dysfunction of bladderNeuromuscular dysfunction of bladder, unspecifiedNeuromuscular scoliosis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT05006807
Type
Device Trial
About this record

Access comprehensive clinical trial information for NCT05006807 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Washington and is currently Recruiting. The study focuses on Neuromuscular Blockade. Target enrollment is 100 participants.

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