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Nasal and Gut Microbiota Combined Clinical Events Predicts the Prognosis of Septic Patients - Trial NCT05143736

Access comprehensive clinical trial information for NCT05143736 through Pure Global AI's free database. This phase not specified trial is sponsored by Zhujiang Hospital and is currently Recruiting. The study focuses on Sepsis,Septic Shock. Target enrollment is 300 participants.

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NCT05143736
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diagnostic test
Trial Details
ClinicalTrials.gov โ€ข NCT05143736
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Nasal and Gut Microbiota Combined Clinical Events Predicts the Prognosis of Septic Patients
Nasal and Gut Microbiota Combined Clinical Events Predicts the Prognosis of Patients With Sepsis: a Prospective, Multicentered, Diagnostic Trial

Study Focus

Sepsis,Septic Shock

gut and nasal microbiota detection

Observational

diagnostic test

Sponsor & Location

Zhujiang Hospital

Dongguan,Guanzhou, China

Timeline & Enrollment

N/A

Jan 10, 2022

Jan 31, 2023

300 participants

Primary Outcome

All-cause death at 28 days

Summary

In this prospective, multicentered , diagnostic trial, nasal and fecal specimens will
 collected from patients with sepsis in two critical care units(ICU) at the enrollment day
 ,the third, seventh, and fourteen days after enrollment or until ICU discharge (whatever come
 first). Total DNA from the nasal and fecal specimens will be extracted, amplified, and
 sequenced to determined the characteristics of gut microbiota and nasal microbiota. Finally,
 the characteristics of gut microbiota and nasal microbiota combined clinical information will
 be used to construct a prediction model to predict the prognosis of sepsis.

ICD-10 Classifications

Septic shock
Other sepsis
Other specified sepsis
Sepsis, unspecified
Sepsis due to other specified staphylococcus

Data Source

ClinicalTrials.gov

NCT05143736

Non-Device Trial