NCT05172479

Prognostic Accuracy of qSOFA, SIRS, and EWSs for In-hospital Mortality in Emergency Department

Name: Clinical Trial NCT05172479
Creator: Aseer Central Hospital
Keywords: Sepsis,Septic Shock, Measurement of qSOFA score, diagnostic test, clinical trial, Bahrain,Kuwait,Oman,Qatar,Saudi Arabia,Turkey,United Arab Emirates

Prognostic Accuracy of qSOFA Score, SIRS Criteria, and EWSs for In-hospital Mortality Among Adult Patients Presenting With Suspected Infection to the Emergency Department (PASSEM): Protocol for an International Multicentre Prospective External Validation Cohort Study

Aseer Central Hospital·ClinicalTrials.gov·diagnostic testCompleted

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Study focus

Disease/Condition: Sepsis,Septic Shock
Drug/Device/Intervention: Measurement of qSOFA score
Study type: Observational
Intervention type: diagnostic test

Sponsor & location

Primary sponsor: Aseer Central Hospital
Location: Ar Rifā',Muharraq,Kuwait,Muscat,Doha,Abha,Khamis Mushait,Dammam,Dhahran,Jubail,Jeddah,Jeddah,Arar,Riyadh,Riyadh,Riyadh,Riyadh,Kocaeli,Abu Dhabi,Dubai, Bahrain,Kuwait,Oman,Qatar,Saudi Arabia,Turkey,United Arab Emirates

Timeline & enrollment

Phase: N/A
Start date: Dec 12, 2021
End date: Sep 11, 2023
Enrollment: 3274 participants

Primary outcome

In-hospital mortality

Summary

Early identification of a patient with infection who may develop sepsis is of utmost importance. Unfortunately, this remains elusive because no single clinical measure or test can reflect complex pathophysiological changes in patients with sepsis. However, multiple clinical and laboratory parameters indicate impending sepsis and organ dysfunction. Screening tools using these parameters can help identify the condition, such as SIRS, quick SOFA (qSOFA), National Early Warning Score (NEWS), or Modified Early Warning Score (MEWS). The 2016 SCCM/ESICM task force recommended using qSOFA, while the 2021 Surviving Sepsis Campaign strongly recommended against its use compared with SIRS, NEWS, or MEWS as a single screening tool for sepsis or septic shock. We hypothesised that qSOFA has greater prognostic accuracy than SIRS and EWS (NEWS/NEWS2/MEWS).

ICD-10 classifications

Septic shockOther sepsisOther specified sepsisSepsis, unspecifiedSepsis due to other specified staphylococcus

Data source

Registry: ClinicalTrials.gov
Trial ID: NCT05172479
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for NCT05172479 through Pure Global AI's free database. This phase not specified trial is sponsored by Aseer Central Hospital and is currently Completed. The study focuses on Sepsis,Septic Shock. Target enrollment is 3274 participants.

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