A Phase 2 Study of Gemtuzumab Ozogamicin (GO)-Gilteritinib Combination in Adults With FLT3-ITD Relapse/Refractory (R/R) AML
- Disease/Condition
- AML
- Drug/Device/Intervention
- Gemtuzumab ozogamicine - Cytarabine - Gilteritinib
- Study type
- Interventional
- Intervention type
- combination product
- Primary sponsor
- Centre Antoine Lacassagne
- Phase
- Phase 2
- Start date
- Mar 31, 2023
- End date
- Mar 15, 2027
- Enrollment
- 50 participants
Stage 1 - Safety of the addition of gilteritinib to the AGORA treatment platform,Stage 2 - Event-free survival (EFS)
This is a national, open-label, single-arm, multicenter phase II trial evaluating the safety
 and efficacy of adding gilteritinib, a new FLT3 inhibitor to the AGORA platform, consisting
 of the combination of an intermediate dose of cytarabine and a divided dose of GO in adult
 patients with R / R AML with an FLT3-ITD mutation.
- Registry
- ClinicalTrials.gov
- Trial ID
- NCT05199051
- Type
- Non-Device Trial
Access comprehensive clinical trial information for NCT05199051 through Pure Global AI's free database. This Phase 2 trial is sponsored by Centre Antoine Lacassagne and is currently Not yet recruiting. The study focuses on AML. Target enrollment is 50 participants.
This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.