NCT05266560

Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Effects of ECT in Depressive Patients

Name: Clinical Trial NCT05266560
Creator: First Affiliated Hospital of Chongqing Medical University
Keywords: Depressive Disorder, ciprofol, Early Phase 1, drug, clinical trial

Effects of Ciprofol Anesthesia on Learning and Memory Function and Antidepressant Efficacy of ECT in Patients With Depression

First Affiliated Hospital of Chongqing Medical University·Early Phase 1·ClinicalTrials.gov·drugNot yet recruiting

View on ClinicalTrials.gov →

Study focus

Disease/Condition: Depressive Disorder
Drug/Device/Intervention: ciprofol
Study type: Interventional
Intervention type: drug

Sponsor & location

Primary sponsor: First Affiliated Hospital of Chongqing Medical University

Timeline & enrollment

Phase: Early Phase 1
Start date: Mar 01, 2022
End date: Dec 31, 2024
Enrollment: 390 participants

Primary outcome

Cognitive impairment rate within 24 hours after the whole ECT course

Summary

In this clinical study, propofol was used as the positive control, and a randomized controlled trial design was used to observe the effects of ciprofol anesthesia on learning and memory function and antidepressant efficacy in patients with ECT. A total of 390 depressed patients who were to undergo electroconvulsive therapy were selected and randomly divided into two groups, namely the propofol group (n=195 cases) and the ciprofol group (n=195 cases). The patients in the propofol group were given propofol 1.5mg/kg + succinylcholine 1mg/kg, and the patients in the ciprofol group were given ciprofol 0.4mg/kg and succinylcholine 1mg/kg, and the patients were given electroshock after anesthesia treat.

ICD-10 classifications

Depressive conduct disorderRecurrent depressive disorder, unspecifiedRecurrent depressive disorderOther recurrent depressive disordersRecurrent depressive disorder, currently in remission

Data source

Registry: ClinicalTrials.gov
Trial ID: NCT05266560
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for NCT05266560 through Pure Global AI's free database. This Early Phase 1 trial is sponsored by First Affiliated Hospital of Chongqing Medical University and is currently Not yet recruiting. The study focuses on Depressive Disorder. Target enrollment is 390 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.