Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST): Prospective COVID-19 Natural History Study - Trial NCT05484882
Access comprehensive clinical trial information for NCT05484882 through Pure Global AI's free database. This phase not specified trial is sponsored by National Human Genome Research Institute (NHGRI) and is currently Recruiting. The study focuses on Heart Disease. Target enrollment is 650 participants.
This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.
Study Focus
Observational
Sponsor & Location
National Human Genome Research Institute (NHGRI)
National Institutes of Health Clinical Center (CC)
Timeline & Enrollment
N/A
Nov 14, 2022
Jun 03, 2030
Primary Outcome
Define the effect of SARS-CoV-2 infection and the development of COVID-19 on vascular function (e.g., pulse wave velocity).,Examine how social factors influence the effect of SARS-CoV-2 and COVID-19 on vascular function.,Define the effect of social factors (e.g., socio-economic status; neighborhood characteristics) on exposure to SARS-CoV-2 and the development of COVID-19
Summary
Background:
 
 The COVID-19 pandemic infected and killed African Americans at higher rates than other
 Americans. Researchers want to understand why.
 
 Objective:
 
 This natural history study will look at how genetic, environmental, and social factors may
 predict or affect COVID-19 in African Americans. Information from this study will be combined
 with data from the GENE-FORECAST study.
 
 Eligibility:
 
 African Americans who were previously enrolled in GENE-FORECAST.
 
 Design:
 
 The study includes a telephone interview and 1 visit to the NIH clinic. Participants may
 engage in either one or both of these activities.
 
 The telephone interview will last 20 minutes. Participants will talk about their experiences
 during the COVID-19 pandemic.
 
 The clinic visit will last up to 4 hours.
 
 Participants will have a physical exam. They will have blood and urine tests.
 
 They will be tested for COVID-19. A long swab will be inserted into a nostril to get a fluid
 sample from the back of the nose.
 
 They will have noninvasive tests of their blood vessels. One device used is a pen-like probe
 placed lightly on the wrist. Another is a rubber sleeve placed around a finger while a blood
 pressure cuff is used on the arm.
 
 Participants will have a test to measure the electrical activity in their heart. Stickers
 attached to wires will be placed on their chest, arms, and legs.
 
 Participants will answer more questions about COVID-19. They will talk about their health
 behavior. They will talk about their family's health and the neighborhood they live in. Other
 questions will ask how they feel, live, work, and play.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT05484882
Non-Device Trial