NCT05632107

Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor

Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor:a Pilot Study
Huazhong University of Science and Technology·ClinicalTrials.gov·device·Device trialRecruiting
View on ClinicalTrials.gov
Study focus
Disease/Condition
Neuromuscular Blockade
Drug/Device/Intervention
TOF-Watch®;DELSYS® Wireless surface EMG
Study type
Observational
Intervention type
device
Sponsor & location
Primary sponsor
Huazhong University of Science and Technology
Location
Wuhan,Wuhan, China
Timeline & enrollment
Phase
N/A
Start date
Feb 01, 2023
End date
Dec 31, 2025
Enrollment
100 participants
Primary outcome

Assessing the correlation between the train-of-four (TOF) obtained from the 2 devices,Assessing the correlation between the posttetanic count (PTC) obtained from the 2 devices

Summary

A quantitative neuromuscular monitoring device is desirable to titrate the depth of
 neuromuscular block (NMB) during a procedure, and to prevent residual effects after removal
 of the endotracheal tube. Unfortunately, the most widely used monitoring technique
 acceleromyography (AMG) typically implies a series of cumbersome installation and calibration
 procedures that frequently precludes correct use of these devices in clinical practice.
 Electromyography (EMG) has recently attracted a lot of attention as an alternative strategy
 to compensate for the deficiency of AMG-based neuromuscular monitors. Nowadays, a new
 technology that allows for the simultaneous acquisition of EMG and AMG signals is
 commercially available. Although its reliability has been rapidly accepted in Physical
 Medicine and Rehabilitation, the use of the technique in neuromuscular monitoring has never
 been reported. The aim of the present study is to assess the validity of the new device for
 estimating the neuromuscular block by comparing with TOF Watch®-SX, which is the most widely
 accepted AMG-based neuromuscular monitor that has been practiced in the clinical arena for
 decades.

ICD-10 classifications
Skeletal muscle relaxants [neuromuscular blocking agents]Poisoning: Skeletal muscle relaxants [neuromuscular blocking agents]Other neuromuscular dysfunction of bladderNeuromuscular dysfunction of bladder, unspecifiedNeuromuscular scoliosis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT05632107
Type
Device Trial
About this record

Access comprehensive clinical trial information for NCT05632107 through Pure Global AI's free database. This phase not specified trial is sponsored by Huazhong University of Science and Technology and is currently Recruiting. The study focuses on Neuromuscular Blockade. Target enrollment is 100 participants.

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