Upper Extremity Versus Lower Extremity Accessory Access Sites During Transcatheter Aortic Valve Implantation

Clinically relevant bleeding of the randomized access site; either diagnostic or pacemaker access site, or both

The goal of this prospective, multicenter, investigator-initiated, randomized clinical trial
 is to assess the safety and efficacy of a 'minimally invasive, upper extremity' approach
 versus the standard 'lower extremity' approach for accessory access sites in patients
 undergoing a transcatheter aortic valve implantation.
 
 The main questions it aims to answer are whether a 'minimally invasive, upper extremity'
 approach as compared with the standard 'lower extremity' approach:
 
 - Is associated with less clinically relevant access site-related bleeding complications.
 
 - Is associated with a shorter time to mobilization after TAVI.
 
 - Is associated with a shorter duration of hospitalization.
 
 - Has the same early safety outcomes at 30 days post-TAVI.
 
 Participants will be subject to the usual care surrounding a TAVI procedure but will also
 will be asked to fill out two questionnaires before and after TAVI:
 
 - Quick Disabilities of the Arm, Shoulder and Hand (Quick DASH)
 
 - Lower Extremity Functional Scale (LEFS)
 
 Researchers will compare the minimally invasive, upper extremity group with the standard
 lower extremity to see if there are difference regarding the posed questions.