NCT05777512

Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Preterm Infants

Name: Clinical Trial NCT05777512
Creator: Boston Children's Hospital
Keywords: Bronchopulmonary Dysplasia, Gastric Feeds, procedure, clinical trial

A Randomized Controlled Crossover Trial of Postpyloric Versus Gastric Feedings to Improve Pulmonary Outcomes in High-risk Preterm Infants

Boston Children's Hospital·ClinicalTrials.gov·procedureNot yet recruiting

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Study focus

Disease/Condition: Bronchopulmonary Dysplasia
Drug/Device/Intervention: Gastric Feeds
Study type: Interventional
Intervention type: procedure

Sponsor & location

Primary sponsor: Boston Children's Hospital

Timeline & enrollment

Phase: N/A
Start date: Apr 01, 2023
End date: Feb 01, 2026
Enrollment: 50 participants

Primary outcome

Change in modified respiratory severity score (mRSS),Tracheal Aspirates

Summary

The purpose of this study is to determine if postpyloric feedings effectively improve objective measures of pulmonary health in preterm infants with chronic lung disease when compared with nasogastric (NG) feedings. This research will (1) determine the optimal nutritional management to prevent a common and costly complication of prematurity, and (2) use a novel crossover design that examines outcomes of clinical endpoints alongside biomarkers.

ICD-10 classifications

Bronchopulmonary dysplasia originating in the perinatal periodCongenital bronchomalaciaBronchopneumonia, unspecifiedOther congenital malformations of bronchusDiseases of bronchus, not elsewhere classified

Data source

Registry: ClinicalTrials.gov
Trial ID: NCT05777512
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for NCT05777512 through Pure Global AI's free database. This phase not specified trial is sponsored by Boston Children's Hospital and is currently Not yet recruiting. The study focuses on Bronchopulmonary Dysplasia. Target enrollment is 50 participants.

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