Diode Laser and Photodynamic Therapy Vs. Ciclopirox.

Efficacy of treatment of onychomycosis with diode laser combined with photodynamic therapy versus Ciclopirox Hydroxypropyl Chitosan (HPCH) Nail Lacquer.,Efficacy of treatment of onychomycosis with diode laser combined with photodynamic therapy versus Ciclopirox Hydroxypropyl Chitosan (HPCH) Nail Lacquer.,Efficacy of treatment of onychomycosis with diode laser combined with photodynamic therapy versus Ciclopirox Hydroxypropyl Chitosan (HPCH) Nail Lacquer.

The main objective of this study is to compare the efficacy of treatment of onychomycosis by:
 diode laser combined with photodynamic therapy, and topical treatment with Ciclopirox
 Hydroxypropyl Chitosan (HPCH) Nail Lacquer.
 
 The study is a low-intervention, randomised controlled clinical trial. Patient recruitment
 will be done by including in the sample those patients who have diagnostic confirmation of
 onychomycosis in the Chiropodology and Surgery Service of the University Podiatry Clinic of
 the Complutense University of Madrid. Participants in the trial will be assigned with equal
 probability to each treatment arm, according to their consecutive inclusion in the study.
 Subsequently, treatment assignment will be determined by a random code. The treatment used
 will be evident to both the participant and the podiatrist responsible for the intervention.
 
 Visits will be made every 7 days at the start of treatment and for 9 weeks in group 1
 (treatment with laser and photodynamic therapy), and monthly visits in group 2 (treatment
 with ciclopirox nail polish) during the 12 months of follow-up. Regardless of the follow-up
 week at which healing occurs, all patients will be reviewed at 3, 6, 9 and 12 months after
 the first visit.