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The Effect of NADPH Oxidase and Creatine Supplementation on Microvascular Blood Flow Regulation - Trial NCT06018480

Access comprehensive clinical trial information for NCT06018480 through Pure Global AI's free database. This phase not specified trial is sponsored by Florida State University and is currently Recruiting. The study focuses on Endothelial Dysfunction. Target enrollment is 10 participants.

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NCT06018480
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Trial Details
ClinicalTrials.gov โ€ข NCT06018480
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The Effect of NADPH Oxidase and Creatine Supplementation on Microvascular Blood Flow Regulation
NADPH Oxidase Affects on Blood Flow After Administering a High Carbohydrate Meal Pre- and Post-creatine Monohydrate Supplementation.

Study Focus

Endothelial Dysfunction

Creatine Monohydrate

Interventional

other

Sponsor & Location

Florida State University

Tallahassee, United States of America

Timeline & Enrollment

N/A

Aug 29, 2023

Apr 01, 2025

10 participants

Primary Outcome

Concentrations of reactive oxygen species (ROS),Rate of skeletal muscle blood flow,Flow mediated dilation percentage

Summary

This research study seeks to determine the effects of an enzyme in the human body called
 NADPH oxidase (NOX) on blood flow. In addition, the study will investigate the benefits of
 creatine monohydrate, a common sports performance supplement, on blood food and vessel
 function. Participants will undergo two study arms, one in which they consume a high
 carbohydrate meal pre- and post-creatine monohydrate supplementation and one in which they
 will consume a high carbohydrate meal pre- and post-placebo supplementation. Blood flow and
 endothelial function will be assessed before and for 4 hours following the consumption of a
 high-carbohydrate meal pre and post-supplementation (creatine monohydrate and placebo).

ICD-10 Classifications

Other peripheral vascular diseases
Atherosclerosis of arteries of extremities
Other specified peripheral vascular diseases
Renovascular hypertension
Other disorders of arteries and arterioles

Data Source

ClinicalTrials.gov

NCT06018480

Non-Device Trial