The Effect of NADPH Oxidase and Creatine Supplementation on Microvascular Blood Flow Regulation

Concentrations of reactive oxygen species (ROS),Rate of skeletal muscle blood flow,Flow mediated dilation percentage

This research study seeks to determine the effects of an enzyme in the human body called
 NADPH oxidase (NOX) on blood flow. In addition, the study will investigate the benefits of
 creatine monohydrate, a common sports performance supplement, on blood food and vessel
 function. Participants will undergo two study arms, one in which they consume a high
 carbohydrate meal pre- and post-creatine monohydrate supplementation and one in which they
 will consume a high carbohydrate meal pre- and post-placebo supplementation. Blood flow and
 endothelial function will be assessed before and for 4 hours following the consumption of a
 high-carbohydrate meal pre and post-supplementation (creatine monohydrate and placebo).