Variability in Microbial Response to Dietary Fiber

Variability in microbial composition as measured by 'alpha diversity',Concentration of SCFA

The goal of this clinical trial is to understand varying in responses to different dietary
 patterns in healthy people who are getting a health screening colonoscopy.
 
 The main questions it aims to answer are:
 
 - What is the variability in the change of the microbes in the gut of (1) a provided diet
 that is high in fiber vs (2) a diet of the participant's choice.
 
 - What is the magnitude of fasting changes in glucose and lipids following the short-term,
 high-fiber feeding period and identify candidate predictive factors (short-chain fatty
 acids, BMI, sex, starting glucose level) for these changes
 
 Participants will be in one of two groups:
 
 1. High-fiber diet group: These participants will have a series of measurements that
 include: blood biochemistries, body composition measured via DEXA, anthropometrics,
 surveys and questionnaires, and collection of fecal samples.
 
 2. Normal diet group: These participants will eat a diet that is of their choosing (ad
 libitum) and will have a series of measurements that include: fecal samples, and
 questionnaires/surveys including food records.