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Correlation Between Preoperative NT-proBNP and Postoperative AKI - Trial NCT06145347

Access comprehensive clinical trial information for NCT06145347 through Pure Global AI's free database. This phase not specified trial is sponsored by Xijing Hospital and is currently Recruiting. The study focuses on Acute Kidney Injury. Target enrollment is 633 participants.

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NCT06145347
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Trial Details
ClinicalTrials.gov โ€ข NCT06145347
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Correlation Between Preoperative NT-proBNP and Postoperative AKI
Correlation Between the Preoperative N-terminal Pro-B-type Natriuretic Peptide and Acute Kidney Injury After Abdominal Surgery: a Single Center Retrospective Cohort Study Based on ERAS Database

Study Focus

Acute Kidney Injury

Observational

Sponsor & Location

Xijing Hospital

Xi'an, China

Timeline & Enrollment

N/A

Jul 10, 2023

Jan 31, 2024

633 participants

Primary Outcome

Incidence of AKI assessed by KDIGO 2012 (Kidney Disease: Improving Global Outcomes)

Summary

Accurate preoperative AKI risk prediction is of great significance for improving patient
 outcomes. The use of preoperative NT-proBNP can provide a more precise assessment of the
 body's fluid load status, guide intraoperative and postoperative fluid management, and thus
 reduce fluid related postoperative complications. Given the potential association between
 ERAS and increased postoperative AKI, we hypothesize that preoperative NT-proBNP may be
 associated with the development of postoperative AKI in ERAS, and can improve the prediction
 of AKI beyond traditional clinical risk factors. This study aims to validate this hypothesis
 and provide evidence for using NT-proBNP to assess AKI risk before non cardiac surgery.
 Improve the predictive ability of clinical predictive models and optimize ERAS protocols to
 prevent postoperative AKI.

ICD-10 Classifications

Injury of kidney
Acute renal failure
Acute renal failure, unspecified
Other acute renal failure
Acute renal failure with tubular necrosis

Data Source

ClinicalTrials.gov

NCT06145347

Non-Device Trial