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A Study of the Tumor Microenvironment Affecting the Efficacy of Immunotherapy for Esophageal Cancer - Trial NCT06219031

Access comprehensive clinical trial information for NCT06219031 through Pure Global AI's free database. This phase not specified trial is sponsored by Renmin Hospital of Wuhan University and is currently Completed. The study focuses on Esophageal Cancer. Target enrollment is 22 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06219031
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Trial Details
ClinicalTrials.gov โ€ข NCT06219031
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A Study of the Tumor Microenvironment Affecting the Efficacy of Immunotherapy for Esophageal Cancer

Study Focus

Esophageal Cancer

no intervention

Observational

other

Sponsor & Location

Renmin Hospital of Wuhan University

Wuhan, China

Timeline & Enrollment

N/A

Dec 01, 2023

Jan 01, 2024

22 participants

Primary Outcome

Immunotherapy efficacy,CRใ€PRใ€SDใ€PD

Summary

This study is a retrospective study of clinical specimens. The study subjects were patients
 with esophageal cancer who received immunotherapy. Tumor tissue specimens surgically removed
 from patients before treatment will be collected primarily. In situ immunohistochemistry and
 multicolor immunofluorescence will be performed. We hypothesize that there are differences in
 lipid metabolism-related proteins in tumor tissues and immune cells in the preexisting tumor
 microenvironment in patients with esophageal cancer prior to immunotherapy, and that there is
 a link between such differences and the efficacy of immunotherapy.

ICD-10 Classifications

Carcinoma in situ: Oesophagus
Malignant neoplasm of oesophagus
Malignant neoplasm: Middle third of oesophagus
Malignant neoplasm: Overlapping lesion of oesophagus
Malignant neoplasm: Upper third of oesophagus

Data Source

ClinicalTrials.gov

NCT06219031

Non-Device Trial