Comparative Effects of IMT Vs EMT Along With AIT in COPD Patients - Trial NCT06308302

Timeline & Enrollment

Primary Outcome

Modified Medical Research Council (mMRC) Dyspnea Scale,6 Minute Walk Test,Karnofsky Performance Scale (KPS),Fatigue Severity Scale (FSS),FEV1,FVC,FEV1/FVC

Summary

Chronic Obstructive Pulmonary Disease (COPD) is the 3rd leading cause of mortality and 7th
 leading cause of ill-health worldwide. It is characterized by persistent and progressive air
 flow resistance with expiratory flow more compromised as compared to inspiratory flow leading
 to CO2 retention and prominent hyperinflation of lungs. The overall effects of COPD on the
 patient's entire body include pulmonary, followed by extra-pulmonary manifestations in which
 musculoskeletal derangements are more pronounced and interfere with daily activities, further
 deteriorating the patient's health. Restricted air flow leads to an increase in shortness of
 breath on slight exertion and early fatigue or exhaustion of respiratory muscles due to over
 work. Literature from the past describes how COPD care has advanced and emphasizes the value
 of pulmonary rehabilitation in addition to medicinal management to treat decadence. Many
 studies show that Inspiratory muscle training has positive effect on ABG's, some PFT's and
 diaphragmatic function. Endurance and strength training improve patient activity of daily
 living and dyspnea.
 
 This study intricate the collation of Respiratory Muscle Training and Aerobic Interval
 Training on functional performance, exertional dyspnea and fatigue level in patients
 diagnosed with COPD. A randomized controlled trial will be integrated with the sample size of
 53 patients which is calculated through epi-tool. Age of selected Patients will fall between
 30-55 years and will be randomly assigned into 2 groups. Group A (Experimental group A) will
 get Inspiratory breather training along-with Aerobic Interval Training, Group B (Experimental
 group B) will get Expiratory muscle training along-with Aerobic Interval Training (Same
 Protocol). Data will be gathered from Pulmonology wards and OPD of selected hospital.
 Clinical Assessment will be incorporated through Karnofsky performance scale, Fatigue
 Severity Scale, MmRC Dyspnea scale, Digital Spirometer, and 6MWT. Pre-intervention assessment
 measures and Post-intervention measures will be noted and results will be compared. Study
 Duration will be of 06 months after approval of synopsis. Data analysis will be done through
 SPSS.
 
 Key words: Aerobic Interval training (AIT), The Breather Device (BD), 6-min walk test (6MWT),
 Fatigue severity scale (FSS), Modified Medical Research Council dyspnea scale (mMRC), Chronic
 Obstructive Pulmonary Disease (COPD).

ICD-10 Classifications