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A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence - Trial NCT06336291

Access comprehensive clinical trial information for NCT06336291 through Pure Global AI's free database. This Phase 2 trial is sponsored by Philogen S.p.A. and is currently Not yet recruiting. The study focuses on Glioblastoma. Target enrollment is 90 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06336291
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06336291
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A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence
A Dose Optimization Study for L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence

Study Focus

Glioblastoma

L19TNF

Interventional

drug

Sponsor & Location

Philogen S.p.A.

Timeline & Enrollment

Phase 2

Jun 01, 2024

Jun 01, 2026

90 participants

Primary Outcome

Adverse Events,Serious Adverse Events,Unacceptable Toxicity,DILI assessment,Survival

Summary

The trial aims to collect safety, efficacy, exposure, dose- response, pharmacokinetic and
 pharmacodynamic information of the combination of L19TNF and lomustine at different dose
 levels in patients with Glioblastoma at progression or recurrence

ICD-10 Classifications

Malignant neoplasm of brain
Malignant neoplasm: Brain, unspecified
Mesothelioma
Malignant neoplasm: Brain stem
Malignant neoplasm: Overlapping lesion of brain

Data Source

ClinicalTrials.gov

NCT06336291

Non-Device Trial