NCT06354452

Effect of Statin Therapy on Sepsis-related Mortality in Intensive Care Unit Patients

Preadmission Use of Statin Therapy and Sepsis-related Mortality in ICU Patients: a Population-based Cohort Study.
Hospital de Granollers·ClinicalTrials.gov·otherCompleted
View on ClinicalTrials.gov
Study focus
Disease/Condition
Sepsis,Septic Shock
Drug/Device/Intervention
Person-level linkage of the database looking for relationship with sepsis survival and previous intake of certain drug families and previous dependence on health services.
Study type
Observational
Intervention type
other
Sponsor & location
Primary sponsor
Hospital de Granollers
Location
Granollers, Spain
Timeline & enrollment
Phase
N/A
Start date
Jan 01, 2018
End date
Jan 31, 2020
Enrollment
59578 participants
Primary outcome

Death due to sepsis

Summary

The average age of patients with sepsis has increased in recent years in parallel with the
 incidence of sepsis. Many of these patients are frail and require various medications for the
 treatment of their chronic diseases. Common treatments, including e.g. sarcopenic drugs
 (statins, sulphonylureas, methyglinides), antioxidants that prevent sarcopenia (allopurinol)
 or immunoregulators (corticosteroids) may influence the survival and functional prognosis of
 these patients. Knowing which drugs influence sepsis survival and to what degree patients who
 survive sepsis have functional deterioration and increased comorbidity and which modifiable
 factors limit this may be essential.

ICD-10 classifications
Septic shockOther sepsisOther specified sepsisSepsis, unspecifiedSepsis due to other specified staphylococcus
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06354452
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06354452 through Pure Global AI's free database. This phase not specified trial is sponsored by Hospital de Granollers and is currently Completed. The study focuses on Sepsis,Septic Shock. Target enrollment is 59578 participants.

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