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NCT06378580Completed

The Prognostic Impact of Surufatinib for the Treatment of Advanced Pancreatic Ductal Adenocarcinoma

Luo CongClinicalTrials.govdrug
Study focus
Disease/Condition
Pancreatic Cancer
Drug/Device/Intervention
Surufatinib combine immune checkpoint inhibitor
Study type
Observational
Intervention type
drug
Sponsor & location
Primary sponsor
Luo Cong
Funder
Zhejiang Cancer Hospital
Location
Hangzhou, China
Timeline & enrollment
Phase
N/A
Start date
Jul 01, 2022
End date
Apr 01, 2024
Enrollment
72 participants
Primary outcome

Median progression-free survival

Summary

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive tumor with a poor prognosis,
 despite the emergence of chemotherapies, unmet medical needs and limited treatment options
 still exist for patients with metastatic PDAC (mPDAC). Surufatinib is a small-molecule
 tyrosine kinase inhibitor that targets vascular endothelial growth factor (VEGFR) 1, 2, 3,
 fibroblast growth factor receptor 1 (FGFR1), and colony stimulating factor 1 receptor
 (CSF-1R), and ex vivo experiments have demonstrated its effect on PC models.
 
 A retrospective analysis of patients with PDAC who underwent surufatinib at Zhejiang Cancer
 Hospital (Hangzhou,China) from July 2022 to July 2023.The database was extracted from the
 preoperative demographics, blood markers, and surgical pathology information of patients
 undergoing surufatinib in the investigators' hospital.

ICD-10 classifications
Malignant neoplasm of pancreasMalignant neoplasm: Pancreas, unspecifiedMalignant neoplasm: Head of pancreasMalignant neoplasm: Tail of pancreasMalignant neoplasm: Other parts of pancreas
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06378580
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06378580 through Pure Global AI's free database. This phase not specified trial is sponsored by Luo Cong and is currently Completed. The study focuses on Pancreatic Cancer. Target enrollment is 72 participants.

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