NCT06379022

Proteomic Analysis of Newly Restored Single Implants

Clinical and Cellular Responses of Tissues at Newly Restored Single Implants Compared to Contralateral Natural Teeth During Their First Year of Functional Loading
Aristotle University Of Thessaloniki·ClinicalTrials.gov·behavioralCompleted
View on ClinicalTrials.gov
Study focus
Drug/Device/Intervention
Plaque control
Study type
Observational
Intervention type
behavioral
Sponsor & location
Primary sponsor
Aristotle University Of Thessaloniki
Location
Thessaloniki, Greece
Timeline & enrollment
Phase
N/A
Start date
Dec 03, 2018
End date
Nov 29, 2019
Enrollment
10 participants
Primary outcome

Probing pocket depth,Protein expression

Summary

In 10 systemically healthy non-smokers, free of periodontitis, one newly restored implant
 (baseline-T0) and one corresponding tooth were followed over 12 months (T1). All implants
 were screw-retained, and platform-switched. Oral hygiene was closely monitored during the
 study. Probing pocket depth (PPD), attachment levels (CAL), bleeding and plaque indices and
 crevicular fluid were collected from an implant-site (PICF) and a tooth-site (GCF). Total
 proteomic profiles in PICF and GCF were investigated using label-free quantitative
 proteomics.

ICD-10 classifications
Other periodontal diseasesGingivitis and periodontal diseasesPeriodontal disease, unspecifiedChronic periodontitisPeriodontosis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06379022
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06379022 through Pure Global AI's free database. This phase not specified trial is sponsored by Aristotle University Of Thessaloniki and is currently Completed. The study focuses on Peri-Implantitis,Peri-implant Mucositis,Periodontal Diseases. Target enrollment is 10 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.