Pure Global
NCT06390878

Nationwide Research on the Rewilding of Kindergarten Yards

Nationwide Research on the Rewilding of Kindergarten Yards - Vahvistu
Natural Resources Institute Finland·ClinicalTrials.gov·biologicalRecruiting
View on ClinicalTrials.gov →
Study focus
Disease/Condition
Microbial Colonization,Atopic Dermatitis,Asthma in Children,Allergy,Cognitive Change,Respiratory Infection,Nature, Human
Drug/Device/Intervention
Biodiversity
Study type
Interventional
Intervention type
biological
Sponsor & location
Primary sponsor
Natural Resources Institute Finland
Location
Helsinki,Tampere, Finland
Timeline & enrollment
Phase
N/A
Start date
May 01, 2024
End date
Aug 30, 2027
Enrollment
320 participants
Primary outcome

Skin Gammaproteobacteria

Summary

Biodiversity is essential for nature and human well-being. Land use has reduced biodiversity
 in cities that is associated with altered commensal microbiota and a rising burden of
 immunological disorders among urban children.
 
 The investigators will estimate how rewilding of kindergarten yards affects commensal
 microbiome, prevalence of allergies, asthma, atopic dermatitis and infections, cortisol
 levels, cognitive skills and plasma cytokine levels of children.
 
 Our specific aims are:
 
 To assess if rewilding diversifies health-associated skin, saliva and gut microbiota and
 reduces infectious diseases and atopic or allergic symptoms.
 
 Assess whether the rewilding has positive effects on cognitive skills. Assess whether the
 rewilding changes cortisol and plasma cytokine levels. The investigators will recruit
 altogether 320 (160 per treatment) study subjects aged between 1-5 to questionnaire study
 (Task 2), from which 120 study subjects will be analyzed more detailed using microbiological
 and blood samples (Task 1).

ICD-10 classifications
Other atopic dermatitisAtopic dermatitisAtopic dermatitis, unspecifiedPersonal history of allergy, other than to drugs and biological substancesPersonal history of allergy to other antibiotic agents
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06390878
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06390878 through Pure Global AI's free database. This phase not specified trial is sponsored by Natural Resources Institute Finland and is currently Recruiting. The study focuses on Microbial Colonization,Atopic Dermatitis,Asthma in Children,Allergy,Cognitive Change,Respiratory Infection,Nature, Human. Target enrollment is 320 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.