NCT06398548

Impact of Exercise Intensity on Fitness, Extracellular Vesicles, Inflammation, and Metabolism

The Impact of 6 Weeks of Moderate- and Heavy-intensity Continous Training on Peak Oxygen Uptake, Plasma Extracellular Vesicles and Inflammatory Cytokines
University of British Columbia·ClinicalTrials.gov·otherRecruiting
View on ClinicalTrials.gov
Study focus
Disease/Condition
Exercise Training
Drug/Device/Intervention
Control Group
Study type
Interventional
Intervention type
other
Sponsor & location
Primary sponsor
University of British Columbia
Location
Kelowna, Canada
Timeline & enrollment
Phase
N/A
Start date
May 01, 2023
End date
Mar 01, 2025
Enrollment
50 participants
Primary outcome

Peak oxygen uptake

Summary

Introduction
 
 This study investigates the effects of different intensities of indoor cycling on various
 health measures. Participants will perform a maximal cycling test to determine their maximal
 fitness - a strong predictor of overall health - before and after a 6-week training
 intervention. Blood samples will also be obtained to look at various physiological markers
 related to extracellular vesicles, inflammation, and metabolism.
 
 Who can participate?
 
 Healthy young adults who between 18 and 40, are free of immune disease, with a normal body
 mass index can join this study. They will be divided into three groups:
 
 - One group will ride a bike at a moderate pace.
 
 - Another group will ride a bike at a slightly harder pace.
 
 - The third group won't change their usual daily activities and will continue living as
 they normally do.
 
 What does the study involve?
 
 Each exercise session aims to burn a specific amount of calories: 350 for males and 300 for
 females. Participants cycle 3 times a week for 6 weeks. At the end, we'll repeat the bike
 test and take another blood sample to see if there have been any changes due to the exercise.
 
 Why is this research being done?
 
 The researchers want to see how different intensities of exercise impact health and fitness.
 This may help people make better choices about how much and what type of exercise they should
 do.
 
 What happens after the study?
 
 Researchers will analyze the data from the study and see if any differences exist between the
 protocols. If the participant is interested, we will also provide their blood test results,
 and the results from their max test.

ICD-10 classifications
Orthoptic trainingLack of physical exerciseOther physical therapyCardiac rehabilitationExhaustion due to excessive exertion
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06398548
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06398548 through Pure Global AI's free database. This phase not specified trial is sponsored by University of British Columbia and is currently Recruiting. The study focuses on Exercise Training. Target enrollment is 50 participants.

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