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Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases - Trial NCT06401824

Access comprehensive clinical trial information for NCT06401824 through Pure Global AI's free database. This Phase 2 trial is sponsored by Maastricht University Medical Center and is currently Not yet recruiting. The study focuses on NSCLC Stage IV,Brain Metastases, Adult. Target enrollment is 25 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06401824
Phase 2
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06401824
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Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases
A Single Arm Phase II Study Evaluating Intracranial Efficacy of Sacituzumab Govitecan (SG) With Bevacizumab in Patients With Active, Asymptomatic Brain Metastases From Non-small Cell Lung Cancer (NSCLC)

Study Focus

Sacituzumab Govitecan-Hziy 180 MG plus bevacizumab

Interventional

drug

Sponsor & Location

Maastricht University Medical Center

Amsterdam,Groningen,Maastricht, Netherlands

Timeline & Enrollment

Phase 2

Jul 01, 2024

Apr 01, 2027

25 participants

Primary Outcome

brain metastases overall response rate (ORR)

Summary

This study will evaluate whether the combination of sacituzumab govitecan (SG) and
 bevacizumab will result in shrinkage of brain metastases from patients with non-squamous
 non-small cell lung cancer (NSCLC), with disease progression on chemotherapy and
 immunotherapy.

ICD-10 Classifications

Malignant neoplasm: Brain, unspecified
Malignant neoplasm of brain
Malignant neoplasm: Cerebral ventricle
Malignant neoplasm: Central nervous system, unspecified
Malignant neoplasm: Overlapping lesion of brain and other parts of central nervous system

Data Source

ClinicalTrials.gov

NCT06401824

Non-Device Trial