NCT06401941

Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition.

Name: Clinical Trial NCT06401941
Creator: Nicolaus Copernicus University
Keywords: Hyperbaric Oxygenation,Oxygen Toxicity,Antioxidants,Oxidative Stress, Hyperbaric Oxygen Therapy, procedure, clinical trial, Poland

The Impact of Staying in Hyperbaric Oxygen Conditions on the Oxidant-antioxidant Balance and the Activities of Selected Lysosomal Enzymes

Nicolaus Copernicus University·ClinicalTrials.gov·procedureCompleted

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Study focus

Disease/Condition: Hyperbaric Oxygenation,Oxygen Toxicity,Antioxidants,Oxidative Stress
Drug/Device/Intervention: Hyperbaric Oxygen Therapy
Study type: Interventional
Intervention type: procedure

Sponsor & location

Primary sponsor: Nicolaus Copernicus University
Location: Bydgoszcz, Poland

Timeline & enrollment

Phase: N/A
Start date: Apr 26, 2016
End date: Dec 31, 2020
Enrollment: 78 participants

Primary outcome

Thiobarbituric acid reactive substances (TBARS),Malondialdehyde (MDA),Conjugated dienes (CD),Catalase (CAT),Superoxide dismutase (SOD),Glutathione peroxidase (GPx)

Summary

The aim of the research project was to investigate the effects of hyperbaric oxygen (HBO) treatment on the redox equilibrium in individuals with different pathological conditions. Both hyperbaric oxygenation and the pathological condition are associated with redox imbalance (oxidative stress), however, HBO is successfully used in the treatment of chronic wounds, e.g., diabetic foot syndrome, as well as in sudden and acute hearing loss, e.g., acute acoustic trauma or idiopathic sudden sensorineural hearing loss.

ICD-10 classifications

Toxic effect: FormaldehydeAnoxic brain damage, not elsewhere classifiedToxic effect: Nitrogen oxidesToxic effect: Carbon dioxidePoisoning: Vitamins, not elsewhere classified

Data source

Registry: ClinicalTrials.gov
Trial ID: NCT06401941
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for NCT06401941 through Pure Global AI's free database. This phase not specified trial is sponsored by Nicolaus Copernicus University and is currently Completed. The study focuses on Hyperbaric Oxygenation,Oxygen Toxicity,Antioxidants,Oxidative Stress. Target enrollment is 78 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.