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NCT06411977

Effect of Dietary Supplements on the Oral Microbiome

Multiband-/-Bracket Induced Qualitative and Quantitative Changes in the Oral Microbiome and Its Influence by Preventive Intervention Using Dietary Supplements
University Center of Dental Medicine Switzerland·ClinicalTrials.gov·dietary supplementRecruiting
View on ClinicalTrials.gov →
Study focus
Disease/Condition
Nutrition, Healthy
Drug/Device/Intervention
Vegetable juice
Study type
Interventional
Intervention type
dietary supplement
Sponsor & location
Primary sponsor
University Center of Dental Medicine Switzerland
Location
Würzburg,Basel, Germany,Switzerland
Timeline & enrollment
Phase
N/A
Start date
Jul 03, 2020
End date
Aug 01, 2024
Enrollment
22 participants
Primary outcome

Investigation of gingival indices using Plaque Index (PI),Investigation of gingival indices using Periodontal Screening Index (PSI).,Investigation of gingival indices using Sulcus Bleeding Index.,To count the number of bacterial colonization on tongue using next-generation-sequencing of the bacterial 16S rRNA gene.,To count the number of bacterial colonization in plaque using next-generation-sequencing of the bacterial 16S rRNA gene.,To count the number of bacterial colonization in saliva using next-generation-sequencing of the bacterial 16S rRNA gene.

Summary

The oral cavity's microbiome is a diverse community, hosting over 700 bacterial species. Due
 to its varied niches, the oral cavity constitutes a highly complex environment where
 different microbes preferentially colonize distinct habitats.
 
 The aim of the study was to investigate the alteration of the oral microbiome during therapy
 with fixed orthodontic appliances using dietary supplements.

ICD-10 classifications
Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmfulMalnutritionObesitySequelae of malnutrition and other nutritional deficienciesNutritional deficiency, unspecified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06411977
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06411977 through Pure Global AI's free database. This phase not specified trial is sponsored by University Center of Dental Medicine Switzerland and is currently Recruiting. The study focuses on Nutrition, Healthy. Target enrollment is 22 participants.

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