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Prevalence of Emerging Treatment-induced Mutations in Metastatic ER-positive Breast Cancer. - Trial NCT06417801

Access comprehensive clinical trial information for NCT06417801 through Pure Global AI's free database. This phase not specified trial is sponsored by AstraZeneca and is currently Not yet recruiting. The study focuses on Metastatic Breast Cancer. Target enrollment is 70 participants.

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NCT06417801
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Trial Details
ClinicalTrials.gov โ€ข NCT06417801
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Prevalence of Emerging Treatment-induced Mutations in Metastatic ER-positive Breast Cancer.
PANGEIA-2: Prevalence of Emerging Treatment-induced Mutations in metastaticER Positive Breast Cancer.

Study Focus

Metastatic Breast Cancer

Observational

Sponsor & Location

AstraZeneca

Sรฃo Paulo, Brazil

Timeline & Enrollment

N/A

Oct 01, 2024

Dec 01, 2024

70 participants

Primary Outcome

Prevalence of emerging ESR1 mutations

Summary

Observational study on prevalence of emerging ESR1 mutations in liquid biopsy in two cohorts
 of patients with breast cancer (with and without prior therapies in metastatic setting) in
 comparison with patient's baseline ESR1 mutation status as defined by tissue profiling.

ICD-10 Classifications

Malignant neoplasm of breast
Malignant neoplasm of breast
Malignant neoplasm: Breast, unspecified
Malignant neoplasm: Central portion of breast
Malignant neoplasm: Overlapping lesion of breast

Data Source

ClinicalTrials.gov

NCT06417801

Non-Device Trial