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NCT06421519

Different Levels of BiPAP

Crossover Study of the Work of Breathing at Different Levels of BiPAP Settings in Neonates
King's College Hospital NHS Trust·Phase 1/2·ClinicalTrials.gov·otherRecruiting
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Study focus
Disease/Condition
Bronchopulmonary Dysplasia
Drug/Device/Intervention
BiPAP setting
Study type
Interventional
Intervention type
other
Sponsor & location
Primary sponsor
King's College Hospital NHS Trust
Location
London, United Kingdom
Timeline & enrollment
Phase
Phase 1/2
Start date
May 10, 2024
End date
Aug 01, 2024
Enrollment
21 participants
Primary outcome

Work of breathing,Work of breathing

Summary

Some infants with breathing problems at birth may need to be connected to a machine to help
 support their breathing. The purpose of this study is to optimise the level of breathing
 support on Bi level continuous airway pressure (BiPAP), a support which gives two levels of
 support (pressure) to premature infants.
 
 The study is investigating which upper pressure gives the best support, that is results in
 the baby having to breathe less hard (work of breathing).
 
 Researchers will measure the work of breathing using a small catheter. Infants will receive
 three different upper pressures of BiPAP with the same baseline pressure for 20 minutes each.
 In between each upper level they will receive the standard upper pressure for 20 minutes.

ICD-10 classifications
Bronchopulmonary dysplasia originating in the perinatal periodCongenital bronchomalaciaBronchopneumonia, unspecifiedOther congenital malformations of bronchusDiseases of bronchus, not elsewhere classified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06421519
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06421519 through Pure Global AI's free database. This Phase 1/2 trial is sponsored by King's College Hospital NHS Trust and is currently Recruiting. The study focuses on Bronchopulmonary Dysplasia. Target enrollment is 21 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.