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An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures - Trial NCT06422221

Access comprehensive clinical trial information for NCT06422221 through Pure Global AI's free database. This Phase 4 trial is sponsored by University of Santiago de Compostela and is currently Not yet recruiting. The study focuses on Bacteremia,Endocarditis. Target enrollment is 150 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.

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NCT06422221
Phase 4
Not yet recruiting
drug
Trial Details
ClinicalTrials.gov โ€ข NCT06422221
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An Oral Doxycycline Regimen to Prevent Bacteremia Following Dental Procedures

Study Focus

Bacteremia,Endocarditis

Clindamycin

Interventional

drug

Sponsor & Location

University of Santiago de Compostela

Santiago De Compostela, Spain

Timeline & Enrollment

Phase 4

May 14, 2024

Jun 30, 2025

150 participants

Primary Outcome

Bacteremia in participants receiving a prophylactic dosage with oral doxycyclin

Summary

Although controversy exists regarding the efficacy of antibiotic prophylaxis for patients at
 risk of infective endocarditis, expert committees continue to publish recommendations for
 antibiotic prophylactic regimens. The last American Heart Association (AHA) and European
 Society of Cardiology (ESC) guidelines include several important changes, highlighting that
 clindamycin (CLI) is no longer recommended as an alternative to amoxicillin in those allergic
 to penicillin. This new project aims to evaluate the effectiveness of oral doxycycline in
 preventing post-dental extraction bloodstream infection.

ICD-10 Classifications

Candidal endocarditis
Acute endocarditis, unspecified
Acute and subacute infective endocarditis
Acute and subacute endocarditis
Myocarditis in bacterial diseases classified elsewhere

Data Source

ClinicalTrials.gov

NCT06422221

Non-Device Trial