PACTR2009040001261177

Optimization of tuberculosis and HIV co-treatment in Africa

Name: Clinical Trial PACTR2009040001261177
Creator: Karolinska institutet; Karolinska institutet
Keywords: Infections and Infestations; Infections and Infestations, Not Applicable, drug, clinical trial, Tanzania;Ethiopia

Pharmacokinetic, pharmacogenetic aspects on drug-drug interactions between rifampicin and efavirenz

Karolinska institutet; Karolinska institutet·Not Applicable·Pan Africa Clinical Trials Registry·drugRecruiting

Study focus

Disease/Condition: Infections and Infestations; Infections and Infestations
Intervention type: drug

Sponsor & location

Primary sponsor: Karolinska institutet; Karolinska institutet
Funder: The European & Developing Countries Clinical Trials Partnership (EDCTP); The European & Developing Countries Clinical Trials Partnership (EDCTP)
Location: Tanzania;Ethiopia

Timeline & enrollment

Phase: Not Applicable
Start date: Jan 01, 1900
End date: Jan 01, 1900

Summary

Concomitant HIV and TB treatment is complicated due to interaction between rifampicin and efavirenz, cornerstones of anti-TB and HAART respectively. Rifampicin reduces plasma levels of efavirenz. Appropriate efavirenz dosage to be used with rifampicin is uncertain. The study aim to identify safe and effective HAART + TB treatment regimen and optimal efavirenz dose to be used with rifampicin.

ICD-10 classifications

Certain infectious and parasitic diseasesInfestation, unspecifiedOther specified infestationsOther infestationsSequelae of infectious and parasitic diseases

Data source

Registry: Pan Africa Clinical Trials Registry
Trial ID: PACTR2009040001261177
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for PACTR2009040001261177 through Pure Global AI's free database. This Not Applicable trial is sponsored by Karolinska institutet; Karolinska institutet and is currently Recruiting. The study focuses on Infections and Infestations; Infections and Infestations.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to Pan Africa Clinical Trials Registry data, helping medical device and pharmaceutical companies navigate clinical research efficiently.