The pharmacokinetics of lopinavir/ritonavir, nevirapine and efavirenz when given with isoniazid in South African HIV-infected individuals
- Disease/Condition
- Infections and Infestations; Infections and Infestations
- Primary sponsor
- University of Cape Town
- Funder
- South African Medical Research Council
- Location
- South Africa
- Phase
- Not Applicable
- Start date
- Jan 01, 1900
- End date
- Jan 01, 1900
INH has been shown to inhibit various cytochrome P450 (CYP) isoforms including CYP3A4.IPT and ART have complementary roles for tuberculosis prevention and is likely to be a priority intervention as part of of HIV treatment. We propose to study the pharmacokinetics of INH when administered with ART, specifically NVP, EFV and LPV/r.
- Registry
- Pan Africa Clinical Trials Registry
- Trial ID
- PACTR201206000391313
- Type
- Non-Device Trial
Access comprehensive clinical trial information for PACTR201206000391313 through Pure Global AI's free database. This Not Applicable trial is sponsored by University of Cape Town and is currently Recruiting. The study focuses on Infections and Infestations; Infections and Infestations.
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