PACTR201301000445375

Atorvastastin and HIV associated immune activation

Name: Clinical Trial PACTR201301000445375
Creator: Damalie Nakanjako
Keywords: Infections and Infestations; Nutritional, Metabolic, Endocrine, Not Applicable, drug, clinical trial, Uganda

Use of Atorvastatin among HAART-treated adults with suboptimal immune recovery in Uganda

Damalie Nakanjako·Not Applicable·Pan Africa Clinical Trials Registry·drugCompleted

Study focus

Disease/Condition: Infections and Infestations; Nutritional, Metabolic, Endocrine
Intervention type: drug

Sponsor & location

Primary sponsor: Damalie Nakanjako
Funder: Makerere University Infection and immunity Program; Canadian Grand Challenge
Location: Uganda

Timeline & enrollment

Phase: Not Applicable
Start date: Nov 15, 2012
End date: Jan 24, 2014

Summary

Pre-ART HIV-associated immune activation is associated with increased risk of morbidity and mortality. During HAART, immune activation persists and is associated with suboptimal immune recovery. Anti-immune activation agents may improve immune recovery. This clinical trial will determine the effect of adjuvant therapy with atorvastatin on T-cell immune activation and exhaustion among HAART-treated adults with suboptimal CD4 reconstitution despite viral suppression in an African cohort.

ICD-10 classifications

Endocrine, nutritional and metabolic diseasesPersonal history of endocrine, nutritional and metabolic diseasesBacterial, viral and other infectious agentsCertain infectious and parasitic diseasesOther specified infestations

Data source

Registry: Pan Africa Clinical Trials Registry
Trial ID: PACTR201301000445375
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for PACTR201301000445375 through Pure Global AI's free database. This Not Applicable trial is sponsored by Damalie Nakanjako and is currently Completed. The study focuses on Infections and Infestations; Nutritional, Metabolic, Endocrine.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to Pan Africa Clinical Trials Registry data, helping medical device and pharmaceutical companies navigate clinical research efficiently.