Effect of sodium bicarbonate on the lower respiratory tract pathogens - Trial PACTR201508001233590
Access comprehensive clinical trial information for PACTR201508001233590 through Pure Global AI's free database. This Not Applicable trial is sponsored by Chest medicine department- Mansoura faculty of medicine and is currently Completed. The study focuses on Respiratory; Other.
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Study Focus
Sponsor & Location
Chest medicine department- Mansoura faculty of medicine
no funding source
Timeline & Enrollment
Not Applicable
Mar 12, 2014
May 30, 2015
Summary
All microbes grow within a particular range of external pH. pH had played many key roles in the development of microbiology. Change in local media can occur with infection as local acidosis, the abnormally acidic pH partially inhibited bacterial killing by ASL. In addition, gram-negative bacteria have increased resistance to antimicrobial peptides when grown at low pHThe aim of this work is to evaluate the effect of bronchoalveolar lavage (BAL) with sodium bicarbonate 8.4% versus BAL with saline 0.9% on the retrieved lower respiratory tract pathogens.
ICD-10 Classifications
Data Source
Pan Africa Clinical Trials Registry
PACTR201508001233590
Non-Device Trial