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PACTR202006677216503

Potential therapeutic effect induced by melatonin supplementation and combined physical activity on postural stability and biological responses in obese patients

Acute melatonin ingestion reduced muscle damage, inflammation and oxidative stress after an exhaustive exercise in obese patients.
Research Laboratory molecular bases of human pathology LR19ES13 Faculty of medicine of Sfax; Department of physical medicine and functional rehabilitation Habib Bourguiba University Hospital·Phase 3·Pan Africa Clinical Trials RegistryCompleted
Study focus
Disease/Condition
Nutritional, Metabolic, Endocrine
Sponsor & location
Primary sponsor
Research Laboratory molecular bases of human pathology LR19ES13 Faculty of medicine of Sfax; Department of physical medicine and functional rehabilitation Habib Bourguiba University Hospital
Funder
Habib Bourguiba University Hospital
Location
Tunisia
Timeline & enrollment
Phase
Phase 3
Start date
Mar 12, 2018
End date
May 14, 2018
Summary

It is well documented that intense physical exercise leads to inflammation, oxidative stress and muscle damage especially in obese subjects who are already predisposed to these risks. Melatonin (MLT) is considered an endogenous antioxidant which may have beneficial effects against inflammation, oxidative stress and tissue repair after a workout.The objective of this study was to examine for the first time the effect of MLT on inflammatory parameters, oxidative stress and muscle damage in obese subjects after an exhaustive exercise in obese patients.

ICD-10 classifications
Endocrine, nutritional and metabolic diseasesPersonal history of endocrine, nutritional and metabolic diseasesOther postprocedural endocrine and metabolic disordersFamily history of other endocrine, nutritional and metabolic diseasesPostprocedural endocrine and metabolic disorders, not elsewhere classified
Data source
Registry
Pan Africa Clinical Trials Registry
Trial ID
PACTR202006677216503
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for PACTR202006677216503 through Pure Global AI's free database. This Phase 3 trial is sponsored by Research Laboratory molecular bases of human pathology LR19ES13 Faculty of medicine of Sfax; Department of physical medicine and functional rehabilitation Habib Bourguiba University Hospital and is currently Completed. The study focuses on Nutritional, Metabolic, Endocrine.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to Pan Africa Clinical Trials Registry data, helping medical device and pharmaceutical companies navigate clinical research efficiently.