Real-world results of Zeiss selective laser trabeculoplasty in South African adult glaucoma and ocular hypertension patients. - Trial PACTR202303599487772

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Summary

Aim:To investigate the safety and efficacy of the ZEISS SLT laser in treating open angle glaucoma and ocular hypertension in a real-world clinical practice.Selective laser trabeculoplasty (SLT) has been used as an alternative or supplementary treatment to conventional glaucoma therapy for almost 20 years. The majority of trials done on SLT compared the procedure with medical measures to lower intra-ocular pressure (IOP). This was done either in treatment naïve patients, or in patients who had their medical therapy terminated with a washout period prior to the laser. Very little is published on the effect of SLT patients who are currently on medical treatment, with the aim to decrease their medication load.The purpose of this retrospective study is to evaluate the efficacy and safety profile of the Zeiss SLT laser in glaucoma and ocular hypertension patients who are currently treated with pharmacotherapy. We will aim to prove that following SLT laser, we can decrease the number of IOP lowering agents while maintaining good IOP control in those patients who were well controlled prior to the procedure. Furthermore, in patients who do not meet their target IOP prior to SLT, we aim to establish if theprocedure managed to improve their IOP control.Clinical records of all patients who had the SLT procedure between 1 May 2022 to 31 December 2022 will be examined for eligibility to the trial, whereafter data will be collected, analyzed and published.

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