Magnesium sulphate versus dexmedetomidine for cough suppression during anesthetic emergence in smokers: A randomized double _ blind controlled trial

Cough during the perioperative period is usually transient and self-limiting. On emergence from anesthesia, cough may protect against aspiration. However, cough can also result in perioperative morbidity, including tachyarrhythmia, arterial hypertension, cardiovascular collapse, and airway complications, and it may increase intracranial, intra abdominal, and intraocular pressure .Cigarette smokers known to have respiratory problems during induction of anesthesia with increased incidence of laryngospasm and cough during extubation as the integrity of epithelium lost by smoke irritation.Multiple medications have been shown to reduce emergence coughing, such as lidocaine (i.v., intracuff, topical, and tracheal routes), dexmedetomidine, fentanyl, and remifentanil.The aim of this study is to investigate and compare the effect of dexmedetomidine and magnesium sulphate on the prevention of emergence cough after general anesthesia in smokers performing lower abdominal surgeries.