Hologic Aptima HPV Assay

The Aptima HPV assay is a target amplification nucleic acid probe test for the in vitro qualitative detection of E6/E7 viral messenger RNA (mRNA) from 14 high-risk types of human papillomavirus (HPV) (16/18/31/33/35/39/45/51/52/56/58/59/66/68). The assay does not discriminate between the 14 high-risk types. The assay is indicated for use in screening patients with ASC-US (atypical squamous cells of undetermined significance) Pap test results to determine the need for colposcopy and can be used with cervical cytology to adjunctively screen for high risk HPV types. The assay can be used as a primary screening test, with or without cervical cytology to identify women at increased risk for the development of cervical cancer or presence of high-grade disease. Cervical specimens collected in ThinPrep Pap Test vials containing PreservCyt solution, or with the Aptima Cervical Specimen Collection and Transport Kit, or in SurePath Preservative Fluid can be used.