PMS2 Qualitative Protein Test Kit - Vietnam Registration 2401183ĐKLH/BYT-HTTB

VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody (VENTANA anti-PMS2 (A16-4)) is used in the laboratory to detect the protein PMS2 by immunohistochemistry in formalin-fixed, paraffin-embedded (FFPE) tissue sections using optical microscopy. VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody is available as a ready-to-use reagent on the BenchMark IHC/ISH platform with the OptiView DAB IHC Detection Kit, OptiView Amplification Kit, and associated accessories. VENTANA anti-PMS2 (A16-4) Mouse Monoclonal Primary Antibody is a component of the VENTANA MMR RxDx Panel and VENTANA MMR IHC Panel, which are listed in Table 1. Table 1. Name of the Test and Clinical Application: - VENTANA MMR RxDx Panel (MLH1, PMS2, MSH2 and MSH6): The VENTANA MMR RxDx Panel is indicated to support the determination of patients with mismatch repair deficient (dMMR) endometrial cancer who are eligible for treatment with JEMPERLI (dostarlimab) as per the product label. - VENTANA MMR IHC Panel (MLH1, PMS2, MSH2, MSH6 and BRAF V600E): The VENTANA MMR IHC Panel is indicated for the detection of mismatch repair deficient (dMMR) protein, it is a test to determine individuals at risk for Lynch syndrome in patients diagnosed with colorectal cancer (CRC), and in combination with the BRAF V600E status, it supports the differentiation between sporadic colorectal cancer and colorectal cancer that may be due to Lynch syndrome in the absence of MLH1 protein expression. The results of this test must be interpreted by a qualified pathologist in conjunction with histology, relevant clinical information, and appropriate control samples. This product is intended for in vitro diagnostic use (IVD).