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NCT01004523

Study of Tissue and Blood Samples From Patients With Low-Grade Glioma

Diagnostic and Prognostic Markers in Low-Grade Gliomas
Alliance for Clinical Trials in Oncology·ClinicalTrials.gov·geneticCompleted
View on ClinicalTrials.gov →
Study focus
Disease/Condition
Brain and Central Nervous System Tumors
Drug/Device/Intervention
fluorescence in situ hybridization
Study type
Observational
Intervention type
genetic
Sponsor & location
Primary sponsor
Alliance for Clinical Trials in Oncology
Location
Scottsdale,Jacksonville,Clive,Des Moines,Des Moines,Des Moines,Des Moines,Des Moines,Des Moines,Adrian,Monroe,Monroe,Bemidji,Duluth,Duluth,Duluth,Rochester,Bismarck,Fargo,Fargo,Bowling Green,Elyria,El, United States of America
Timeline & enrollment
Phase
N/A
Start date
Dec 01, 1995
End date
Mar 01, 2013
Enrollment
135 participants
Primary outcome

Alterations in chromosomes 7, 9p, 10, 17, 19q, X, or Y as determined by FISH,Loss of chromosomal materials in chromosomes 9p, 10, 13, 17, or 22 by PCR analysis,Levels of PCNA, Ki-67 (MIB-1), or mutated p53 by immunostaining with monoclonal antibodies,DNA ploidy by FISH and flow cytometry,Percentage of cells in S-phase or G2M-phase as measured by flow cytometry

Summary

RATIONALE: Studying samples of tumor tissue and blood from patients with cancer in the
 laboratory may help doctors learn more about changes that occur in DNA and identify
 biomarkers related to cancer. It may also help doctors predict how patients will respond to
 treatment.
 
 PURPOSE: This research study is looking at tissue and blood samples from patients with
 low-grade glioma.

ICD-10 classifications
Malignant neoplasm: Overlapping lesion of brain and other parts of central nervous systemMalignant neoplasm: Central nervous system, unspecifiedBenign neoplasm of brain and other parts of central nervous systemMalignant neoplasm of brainSecondary malignant neoplasm of other and unspecified parts of nervous system
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT01004523
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT01004523 through Pure Global AI's free database. This phase not specified trial is sponsored by Alliance for Clinical Trials in Oncology and is currently Completed. The study focuses on Brain and Central Nervous System Tumors. Target enrollment is 135 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.