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NCT03086330Completed

Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes Mellitus

Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes Mellitus. A 30-week Randomised, Double-blind, Placebo-controlled Trial
Novo Nordisk A/SPhase 3ClinicalTrials.govdrug
Study focus
Drug/Device/Intervention
Semaglutide
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
Novo Nordisk A/S
Location
Andalusia,Anniston,Glendale,Phoenix,Tempe,Little Rock,La Jolla,Lincoln,Northridge,Edgewater,Maitland,Lawrenceville,Woodstock,Hutchinson,Lexington,Baltimore,Troy,Jefferson City,Albany,Smithtown,West Se, Austria,Canada,Japan,Norway,Puerto Rico,Russian Federation,United States of America
Timeline & enrollment
Phase
Phase 3
Start date
Mar 15, 2017
End date
Aug 06, 2018
Enrollment
302 participants
Primary outcome

Change in HbA1c

Summary

This trial is conducted in Asia, Europe and North America. The aim of the trial is to compare
 the effect of semaglutide s.c. 1.0 mg once-weekly versus placebo as add-on to sodium glucose
 co-transporter-2 inhibitor (SGLT-2i) monotherapy or in combination with either metformin or
 sulfonylurea on glycaemic control after 30 weeks of treatment in subjects with type 2
 diabetes. Subjects will remain on their pre-trial medication.

ICD-10 classifications
Type 2 diabetes mellitusType 2 diabetes mellitus with other specified complicationsType 2 diabetes mellitus with unspecified complicationsType 2 diabetes mellitus without complicationsType 2 diabetes mellitus with multiple complications
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT03086330
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT03086330 through Pure Global AI's free database. This Phase 3 trial is sponsored by Novo Nordisk A/S and is currently Completed. The study focuses on Diabetes,Diabetes Mellitus, Type 2. Target enrollment is 302 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.