Pure Global
NCT05085158

Pathogen Detection in HIV-infected Children With Non-malarial Febrile Illnesses Using Metagenomic Sequencing

Pathogen Detection in HIV-infected Children and Adolescents With Non-malarial Febrile Illnesses Using Metagenomic Next-generation Sequencing Approach in Uganda
Makerere University·ClinicalTrials.govNot yet recruiting
View on ClinicalTrials.gov →
Study focus
Disease/Condition
HIV Infection
Study type
Observational
Sponsor & location
Primary sponsor
Makerere University
Timeline & enrollment
Phase
N/A
Start date
Jun 01, 2022
End date
Oct 01, 2024
Enrollment
200 participants
Primary outcome

Prevalence of microbial pathogens in NMFIs HIV-infected children and adolescents

Summary

In Uganda, 130,000 children (0-14 years of age) were living with HIV in 2018. Last year,
 nearly 450 infants acquired HIV every day; most of them during childbirth and these are at
 extremely high risk of dying in the first two years of life from treatable infections which
 present with fever. While fevers are commonly attributed to malaria, most fevers in African
 children are not due to malaria and clinicians are challenged by the similar clinical
 features of wide spectrum of potential aetiologies. The prevalence of treatable causes of
 non-malarial febrile illnesses in children in Africa has been reported to be 45%.

ICD-10 classifications
HIV disease resulting in other viral infectionsHuman immunodeficiency virus [HIV] diseaseHIV disease resulting in other bacterial infectionsAcute HIV infection syndromeUnspecified human immunodeficiency virus [HIV] disease
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT05085158
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT05085158 through Pure Global AI's free database. This phase not specified trial is sponsored by Makerere University and is currently Not yet recruiting. The study focuses on HIV Infection. Target enrollment is 200 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.