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NCT05091008

Treatment of Chronic Hepatitis C Infection by Ledipasvir/Sofosbuvir in Naïve Children

The Safety and Efficacy of Ledipasvir/Sofosbuvir in the Treatment of Chronic Hepatitis C Virus Infection in Naïve Children
Mansoura University Children Hospital·Phase 2·ClinicalTrials.gov·drugCompleted
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Study focus
Disease/Condition
Hepatitis C, Chronic
Drug/Device/Intervention
Ledipasvir-Sofosbuvir 90 Mg-400 Mg Oral Tablet
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
Mansoura University Children Hospital
Location
Mansoura, Egypt
Timeline & enrollment
Phase
Phase 2
Start date
Mar 01, 2018
End date
Mar 10, 2020
Enrollment
50 participants
Primary outcome

Evaluate the efficacy of Ledipasvir-Sofosbuvir fixed-dose combination one tablet (90 mg Ledipasvir, 400 mg Sofosbuvir), in children with treatment-Naïve, chronic HCV infection, genotype 4.,Evaluate the efficacy of Ledipasvir-Sofosbuvir fixed-dose combination one tablet (90 mg Ledipasvir, 400 mg Sofosbuvir), in children with treatment-Naïve, chronic HCV infection, genotype 4.

Summary

Chronic hepatitis C virus (HCV) infection represents a crucial health problem in children
 that greatly influence their quality of life. Many efforts have been directed toward the
 investment of effective drugs with high safety profiles and with oral administration for
 better compliance. The development of a new direct-acting antiviral (DAA) made it possible to
 achieve these goals.

ICD-10 classifications
Chronic viral hepatitis CAcute hepatitis CChronic hepatitis, unspecifiedChronic viral hepatitisChronic viral hepatitis, unspecified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT05091008
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT05091008 through Pure Global AI's free database. This Phase 2 trial is sponsored by Mansoura University Children Hospital and is currently Completed. The study focuses on Hepatitis C, Chronic. Target enrollment is 50 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.