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NCT05404555Recruiting

Prognostic Value of Right Ventricular Myocardial Strain in Patients With Acute Myocardial Infarction

Prognostic Value of Right Ventricular Myocardial Strain in Patients With Acute Myocardial Infarction With Different Infarction-related Vessels
Peking University Third HospitalClinicalTrials.govother
Study focus
Drug/Device/Intervention
two-dimensional speckle tracking echocardiography
Study type
Observational
Intervention type
other
Sponsor & location
Primary sponsor
Peking University Third Hospital
Location
Beijing, China
Timeline & enrollment
Phase
N/A
Start date
Oct 01, 2021
End date
Oct 30, 2024
Enrollment
200 participants
Primary outcome

Major Adverse Cardiovascular Events

Summary

For a long time, the right ventricle has been the forgotten chamber, but with the deepening
 of people's understanding of the disease, right ventricular dysfunction has become an
 important factor to evaluate the disease progression and late prognosis of patients with AMI.
 Right ventricular myocardial strain derived from two-dimensional speckle tracking
 echocardiography is a new method for early evaluation of regional and global right
 ventricular systolic function, and its repeatability is much higher than that of LVEF. Acute
 inferior myocardial infarction is often caused by occlusion of the proximal middle segment of
 the right coronary artery. Many studies have confirmed that RVMS is an independent predictor
 of poor prognosis in patients with AIMI. However, 60% of the right ventricular systolic
 function is contributed by the left ventricle and interventricular septum, and the left
 anterior descending branch and the left circumflex branch are the main sources of blood
 supply to the left ventricle and interventricular septum, so in theory, non-RCA occlusion can
 also lead to varying degrees of right ventricular dysfunction. However, there are few studies
 on the role of RVMS in predicting the prognosis of AMI patients caused by non-RCA occlusion.
 Therefore, the purpose of this study is to prospectively study the value of dynamic changes
 of RVMS in predicting the prognosis of patients with acute myocardial infarction with
 different infarct-related vessels, in order to provide more clinical reference information
 for the diagnosis and treatment of AMI.

ICD-10 classifications
Acute myocardial infarctionAcute myocardial infarction, unspecifiedAcute subendocardial myocardial infarctionCertain current complications following acute myocardial infarctionOther current complications following acute myocardial infarction
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT05404555
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT05404555 through Pure Global AI's free database. This phase not specified trial is sponsored by Peking University Third Hospital and is currently Recruiting. The study focuses on Acute Myocardial Infarction. Target enrollment is 200 participants.

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